Quality of Life Issues and Treatment in Pancreas Cancer

نویسنده

  • Joseph Markowitz
چکیده

Patients with pancreatic adenocarcinoma face many quality of life issues. Prior to the development of the FOLFIRINOX (5-FU, irinotecan, oxaliplatin, and leucovorin) [1,2] and gemcitabine/ nab-paclitaxel [3] chemotherapeutic regimens the survival of patients with metastatic disease was on the order of 6 months. These two newer regimens increased the overall survival to an average of 11.1 and 8.5 months, respectively. Quality of life should be stabilized at the highest possible level with chemotherapy to postpone deterioration in functional status [4]. It has also been shown that pain and tiredness are independent survival prognostic indicators [5]. For these reasons, treatment for pancreatic cancer must take into account quality of life measures.

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تاریخ انتشار 2014